Colts vs Jaguars Odds, Picks, and Predictions Week 6: Lawrence Dazzles Against Indy's Vulnerable Secondary

The Indianapolis Colts are to face the Jacksonville Jaguars on Sunday in the latest Week 6 odds. The Jaguars are returning home after a two-week stint in London and now square up against a Colts side that will be missing starting quarterback Anthony Richardson.

Despite backup Gardner Minshew taking over under center, money has come in on the visitors and NFL odds for this contest have slimmed from Jaguars -5 to -4.

Should you go against or follow the line movement? I let you know with my best free NFL picks for Colts vs. Jaguars on October 15. 

Colts vs Jaguars odds

Colts vs Jaguars predictions

It’s a pretty rare sight to see an underdog lose its starting quarterback and get fewer points on the sprea…